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11 p, 1.9 MB |
The ATLAS ASMA Study : Assessing the Impact of Asthma on Patients' Life - The Spanish Patients' Perspective
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Domínguez-Ortega, Javier (Hospital Universitario La Paz (Madrid)) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Nieto Garcíá, Antonio (Instituto de Investigación Sanitaria La Fe) ;
Delgado Romero, Julio (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Ancochea, Julio (Instituto de Salud Carlos III) ;
Mejia, Natalia (Novartis Farmacéutica) ;
Pastor, Mariano (Fundación Española de Asociaciones de Pacientes Alérgicos y con Enfermedades Respiratorias) ;
Blanco-Aparicio, Marina (Complejo Hospitalario Universitario de A Coruña) ;
Universitat Autònoma de Barcelona
ATLAS ASMA described the psychosocial impact of asthma on patients' daily life from patients' perspectives (in terms of impaired personal and intimate relationships, sleep quality, leisure time, daily activities, and others) in Spain. [...]
2023 -  10.2147/JAA.S404525
Journal of Asthma and Allergy, Vol. 16 (may 2023) , p. 461-471
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4 p, 302.7 KB |
Improvement in Lung Function with Dupilumab Does Not Predict Its Effects on Reducing Asthma Exacerbation
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Hanania, Nicola A (Baylor College of Medicine) ;
Maspero, Jorge F (Fundación CIDEA) ;
Halpin, David M G (University of Exeter) ;
Jackson, David J (Guy's Severe Asthma Centre, Guy's and St Thomas' NHS Foundation Trust) ;
Panettieri, Reynold A (The State University of New Jersey) ;
Castro, Mario (University of Kansas School of Medicine) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Daizadeh, Nadia (Sanofi) ;
Gall, Rebecca (Regeneron Pharmaceuticals. Inc) ;
Jacob-Nara, Juby A (Sanofi) ;
Ortiz, Benjamin (Regeneron Pharmaceuticals. Inc) ;
Djandji, Michel (Sanofi) ;
Rowe, Paul J (Sanofi) ;
Deniz, Yamo (Regeneron Pharmaceuticals. Inc) ;
Universitat Autònoma de Barcelona
2022 - 10.2147/JAA.S354013
Journal of Asthma and Allergy, Vol. 15 (june 2022) , p. 851-854
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3.
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7 p, 1.3 MB |
The Response to Biologics is Better in Patients with Severe Asthma Than in Patients with Asthma-COPD Overlap Syndrome
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Pérez de Llano, Luis (Pneumology Service. Hospital Lucus Augusti. EOXI Lugo. Cervo e Monforte) ;
Dacal Rivas, David (Hospital Universitario Lucus Augusti (Lugo)) ;
Malanda, Nuria Marina (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Gullón, José Antonio (Hospital Universitario Lucus Augusti (Lugo)) ;
Muñoz-Esquerre, Mariana (Institut d'Investigació Biomèdica de Bellvitge) ;
García-Moguel, Ismael (Allergy Service) ;
Díaz Campos, Rocío Magdalena (Hospital Universitario) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
Harbenau Mena, Alicia (Hospital de Mérida) ;
Cosio, Borja G (Institut d'Investigació Sanitària Illes Balears) ;
Padilla, Alicia (Hospital Costa del Sol (Marbella)) ;
Cisneros, Carolina (Hospital Universitario de la Princesa (Madrid))
Although biologics have demonstrated to be effective in T2-high asthma patients, there is little experience with these drugs in asthma-COPD overlap (ACO). The aim of this study was to compare the effectiveness of biologics in these two conditions. [...]
2022 - 10.2147/JAA.S338467
Journal of Asthma and Allergy, Vol. 15 (2022) , p. 363-369
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4.
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9 p, 875.7 KB |
Characteristics of Induced-Sputum Inflammatory Phenotypes in Adults with Asthma : Predictors of Bronchial Eosinophilia
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Crespo Lessmann, Astrid (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Curto Sánchez, Elena (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Mateus Medina, Eder Freddy (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Palones, Esther (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Belda Soler, Alicia (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Sánchez Maza, Soraya (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Soto-Retes, Lorena (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Plaza, Vicente (Universitat Autònoma de Barcelona. Departament de Medicina)
The objectives of this study were, for patients attending a specialist asthma clinic at a tertiary care hospital, to determine, from sputum induction (SI), proportions of bronchial inflammatory phenotypes, demographic, clinical and functional characteristics of each phenotype, and the most accessible non-invasive inflammatory marker that best discriminates between phenotypes. [...]
2023 - 10.2147/JAA.S389402
Journal of Asthma and Allergy, Vol. 16 (january 2023) , p. 95-103
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15 p, 1.9 MB |
Autoimmune Diseases Are Linked to Type IIb Autoimmune Chronic Spontaneous Urticaria
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Kolkhir, Pavel (Charité - Universitätsmedizin Berlin) ;
Altrichter, Sabine (Charité - Universitätsmedizin Berlin) ;
Asero, Riccardo (Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano) ;
Daschner, Alvaro (Instituto de Investigación Hospital Universitario de la Princesa) ;
Ferrer, Marta (Instituto de Investigación Sanitaria de Navarra) ;
Giménez-Arnau, Ana M 1961- (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Hawro, Tomasz (Charité - Universitätsmedizin Berlin) ;
Jakob, Thilo (Justus Liebig Universität Giessen) ;
Kinaciyan, Tamar (Medical University of Vienna) ;
Kromminga, Arno (Bioagilytix Europe GmbH, Hamburg) ;
Konstantinou, George (424 General Military Training Hospital, Thessaloniki) ;
Makris, Michael (University General Hospital Attikon (Haidari, Grècia)) ;
Metz, Martin (Charité - Universitätsmedizin Berlin) ;
Skov, Per Stahl (RefLab ApS, Copenhagen) ;
Staubach, Petra (University Medical Center Mainz) ;
Sussman, Gordon (University of Toronto) ;
Zhang, Ke (David Geffen School of Medicine at UCLA) ;
Maurer, Marcus (Charité - Universitätsmedizin Berlin)
Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk of comorbid autoimmune diseases. [...]
2021 - 10.4168/aair.2021.13.4.545
Allergy, Asthma & Immunology Research, Vol. 13 (february 2021) , p. 545-559
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7 p, 879.9 KB |
Rupatadine oral solution for 2-5-year-old children with allergic rhinitis : a safety, open-label, prospective study
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Santamaría Masdeu, Eva (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Izquierdo, Iñaki (R&D, J. Uriach y Compañía (Barcelona, Catalunya)) ;
Valle, Marta (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Vermeulen, Jan (Allergic Department, Parow Research, Cape Town, South Africa) ;
Potter, Paul (Allergy Diagnostic and Clinical Research Unit, Department of Medicine, University of Cape Town Lung Institute, Cape Town, South Africa)
There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. [...]
2018 - 10.2147/JAA.S164632
Journal of Asthma and Allergy, Vol. 11 (september 2018) , p. 225-231
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17 p, 1.6 MB |
In Vitro and In Vivo Validation of EP2-Receptor Agonism to Selectively Achieve Inhibition of Mast Cell Activity
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Plaza, Judith (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Torres Blanch, Rosa (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Urbano, Adrián (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Picado, César (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mora Pérez, Fernando de (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Agonism of the prostaglandin E2 receptor, E-prostanoid receptor 2 (EP2), may represent an alternative protective mechanism in mast cell (MC)-mediated diseases. Previous studies have suggested that activation of the MC EP2 receptor prevents pathological changes in the murine models of allergic asthma. [...]
2020 - 10.4168/aair.2020.12.4.712
Allergy, Asthma & Immunology Research, Vol. 12 (april 2020) , p. 712-728
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3 p, 634.4 KB |
Sudan red dye : a new agent causing type-2 occupational asthma
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Clofent, David (Hospital Universitari Vall d'Hebron) ;
de Homdedeu, Miquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muñoz-Esquerre, Mariana (Institut d'Investigació Biomèdica de Bellvitge) ;
Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Sudan red or 1-[(2-methoxyphenyl)azo]-2-naphthol is a low molecular weight azoic agent widely used in industry, particularly in the production of hair dyes. The use of this product in the food industry is prohibited due to its potential carcinogenic effect, but no respiratory involvement has been reported to date. [...]
2020 - 10.1186/s13223-020-0404-8
Allergy, asthma, and clinical immunology, Vol. 16 (january 2020)
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9.
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8 p, 212.0 KB |
Asthma with bronchial hypersecretion : expression of mucins and toll-like receptors in sputum and blood
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Crespo Lessmann, Astrid (Institut d'Investigació Biomèdica Sant Pau) ;
Mateus, Eder (Institut d'Investigació Biomèdica Sant Pau) ;
Torrejón, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ;
Belda Soler, Alicia (Institut d'Investigació Biomèdica Sant Pau) ;
Giner, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Sibila, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
1) Define the clinical and inflammatory phenotype of asthma with bronchial hypersecretion of mucus. 2) Compare the type of mucin present in induced sputum (IS) of patients with and without bronchial hypersecretion. [...]
2017 - 10.2147/JAA.S142200
Journal of Asthma and Allergy, Vol. 10 (october 2017) , p. 269-276
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10.
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7 p, 1.1 MB |
Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma
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Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Ollé Monge, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Vanoirbeek, J. A. (Centre of Environment and Health, KU Leuven) ;
Assialioui, Abdelilah (Hospital Universitari Vall d'Hebron) ;
Gómez Ollés, Susana (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after dermal sensitization in a mouse model. [...]
2016 - 10.1186/s13223-016-0131-3
Allergy, asthma, and clinical immunology, Vol. 12 (May 2016) , art. 26
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